Activity analysis of extracts from palmitoleic acid-producing yeast
  
DOI:10.19902/j.cnki.zgyz.1003-7969.240284
KeyWord:palmitoleic acid  yeast extract  antioxidant activity  tyrosinase inhibitory activity
FundProject:国家重点研发计划(2021YFC2101500);国家级大学生创新创业训练计划项目(202310291080Z)
Author NameAffiliation
TANG Dandan1, SUN Chenjing1, GU Jiawen1, LIN Yinshan1, QIAN Xiujuan1, DONG Weiliang1,2 1.College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, China
2.State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing 211800, China 
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Abstract:
      To investigate the potential and value of palmitoleic acid (POA)-rich yeast extracts for cosmetic applications, the oleaginous yeast Scheffersomyces segobiensis DSM 27193 (with POA synthesis ability) and its modified strain SS-12 were used as research subjects, their oils and POA contents were analyzed, and the polyphenol content, antioxidant activity, and tyrosinase inhibitory activity of the yeast extracts of S. segobiensis DSM 27193 and SS-12 were determined. The results showed that the oils contents of S. segobiensis DSM 27193 and SS-12 were 14.72% and 34.35%, respectively, and the percentages of POA in the oils were 12.03% and 16.00%, respectively. The polyphenol contents of the two yeast extracts could reach up to (3 269±56)μg/mL and (3 546±268)μg/mL, the scavenging rate of DPPH radicals could reach up to 71.70% and 77.38%, the reducing power could reach up to 0.459 and 0.578, and the inhibition rate of tyrosinase could reach up to 91.25% and 99.37%, respectively. In conclusion, both yeast extracts have good antioxidant activity and tyrosinase inhibitory activity, and have an excellent application prospect in the field of cosmetics.
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