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| Effects of diacylglycerol on blood lipid metabolism and body composition of rats with hypercholesterolemia |
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| DOI：10.12166/j.zgyz.1003-7969/2020.03.018 |
| KeyWord:diacylglycerol(DAG) hypercholesterolemia blood lipid body composition fatty liver |
| FundProject:国家自然科学基金（31601398）；佛山市南海区“蓝海人才计划”创新创业团队（201811070001） |
| Author Name | Affiliation | | LUO Jiaxian
ZOU Qiong
ZHU Huilian
YANG Bo
WANG Yonghua | 1.School of Bioscience and Bioengineering, South China University of Technology, Guangzhou 510006，China
2.Guangdong Yue-s Special Nutrition Technology Co., Ltd., Foshan 528000, Guangdong, China
3.School of Public Health, Sun Yat-sen University, Guangzhou 510080,China
4.School of Food Sciences and Engineering, South China University of Technology, Guangzhou 510641, China |
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| Abstract: |
| The rat models of hypercholesterolemia were established with high fat diet and normal rats were adopted as the control group. After the establishment of the model, rats were randomly divided into 2 groups of TAG and diacylglycerol(DAG) based on the total serum cholesterol. The experiment lasted thirty days, and then the changes in total cholesterol(TC), triglyceride(TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and body composition of the rats, as well as the histopathology in rats liver tissue were determined so as to evaluate the effect of DAG on hypercholesterolemia rats. The results showed that DAG had a certain optimization effect on the blood lipid of hypercholesterolemia rats, which showed that DAG could improve serum HDL-C in hyperlipidemia rats, and significantly decrease hepatocellular steatosis. |
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