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| Anti-inflammatory, anti-irritation and anti-eczema effects of high oleic acid sunflower seed oil and oil-tea camellia seed oil |
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| DOI：10.19902/j.cnki.zgyz.1003-7969.230316 |
| KeyWord:high oleic acid sunflower seed oil oil-tea camellia seed oil eczema inflammation 3D epidermal model |
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| Abstract: |
| Aiming to provide data support for the application of oil-tea camellia seed oil and high oleic acid sunflower seed oil in cosmetics,3D epidermal model EpiKutis was used to construct acute injury and eczema-like epidermal models in vitro, the models were treated by cold-pressed high oleic acid sunflower seed oil and oil-tea camellia seed oil, and the anti-inflammatory, anti-irritation and anti-eczema effects of high oleic acid sunflower seed oil and oil-tea camellia seed oil were evaluated by examining the tissue vitality, the release of inflammatory factors, the changes of tissue morphology and structure, and the content of thymus stromal lymphogenesis hormone (TSLP) of the models.The results showed that high oleic acid sunflower seed oil and oil-tea camellia seed oil had no significant effect on tissue vitality, oil-tea camellia seed oil could significantly reduce the release of inflammatory factors, but high oleic acid sunflower seed oil could not. High oleic acid sunflower seed oil and oil-tea camellia seed oil could improve tissue morphology and structure to some extent, and significantly reduce the content of TSLP. To sum up, both oil-tea camellia seed oil and high oleic acid sunflower seed oil have certain inhibition and relief effects on skin irritant inflammation, and have significant anti-eczema effects. At the same time,oil-tea camellia seed oil also has a certain inhibition and relief effect on skin irritant damage. |
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